Drosophila Home      Plenary Platform Workshop Sessions

 
Wednesday, March 27  
9:00 a.m. – 6:00 p.m.
Press Club (Hotel 2nd Floor)

New Faculty Forum



Your first faculty appointment brings many new challenges. Network, learn, and find support at the New Faculty Forum, a one-day workshop designed for new faculty (those within the first five years of their appointment) and advanced postdocs. New this year, participants will have the option to register for different tracks: the basics of teaching and active learning or grant writing. Attendees will discuss common challenges, hear strategies for managing a laboratory, and have opportunities to learn about:

  • tools and techniques for managing budgets effectively;
  • tips for negotiating and establishing relationships with vendors;
  • how to be a supportive mentor;
  • and more!

This focused event will allow you to form a strong network of peers with whom you can continue to collaborate, commiserate, and celebrate long after the meeting ends. A closing networking social will also allow you to connect with more established researchers. Lunch will be provided.
Advanced registration required




 
Wednesday, March 27  
9:00 a.m. – 6:00 p.m.
Pearl 4 (Hotel 2nd Floor)

New Faculty Forum Breakout




 
Wednesday, March 27  
11:00 a.m. – 3:00 p.m.
Austin 2 (Hotel 2nd Floor)

GENETICS Peer Review Training Workshop



This workshop will provide an introduction to peer reviewing for early career researchers, including graduate students. The workshop will cover best practices and a mock review. Becoming a better reviewer will help you to become a better author and to hone some of the skills central to scientific success, including critical thinking, evaluating research, providing helpful feedback, and understanding the mindset and expectations of peer reviewers and editors.  Lunch will be provided.

Advance registration required.




 
Wednesday, March 27  
2:00 p.m. – 5:00 p.m.
Houston Ballroom (Conference Center 3rd Floor)

Ecdysone Workshop



Organizers:
Kim Rewitz
Naoki Yamanaka
 

2:00 PM  Michael Adams, University of California, Riverside, The hormonal triad of ecdysone, ETH, and JH: Influences on physiology and behavior in Drosophila.

2:35 PM  Daniel McKay, University of North Carolina at Chapel Hill, Insights on ecdysone pathway function in developing tissues from genomic profiling.

3:00 PM  Jade Kannangara, Monash University, Neuropeptide F receptor acts in the Drosophila prothoracic gland to regulate growth and developmental timing.

3:15 PM  Kirst King-Jones, University of Alberta, Steroids need Iron: The Drosophila prothoracic gland as a model for studying iron metabolism.

3:40 PM  Yunpo Zhao, Stockholm University, Stop codon readthrough of a POU/Oct transcription factor regulates Drosophila development.

3:55 PM  Jae Park, University of Tennessee, Knoxville, Metamorphosis-induced programmed death of peptidergic neurons.

4:20 PM  Eisuke Imura, University of Tsukuba, Corazonin neurons innervate PTTH neurons and control systemic body growth through basal ecdysteroid regulation in Drosophila.

4:35 PM  Cédric Maurange, Institut de Biologie du Développement de Marseille, Ecdysone-mediated regulation of progenitor self-renewal and tissue regeneration in Drosophila.


The Ecdysone Workshop highlights the diverse roles of insect hormones (e.g., ecdysone, juvenile hormone, peptide hormones and insulin) and hormone receptors in development, growth, metamorphosis, reproduction, and metabolism. Presentations by trainees and new investigators will highlight recent findings in insect endocrinology, and foster discussion among individuals from diverse research interests. Topics include, but are not limited to: hormone synthesis and secretion, hormone-controlled signaling and transcription, cross-talk between hormone signaling pathways, and hormonal control of differentiation, morphogenesis, growth, metabolism, reproduction, and behavior. 


 
Wednesday, March 27  
3:00 p.m. – 6:00 p.m.
Austin 3 (Hotel 2nd Floor)

Grants and Funding



Learn how funding decisions are made.  This program aims to provide attendees important information related to grantsmanship and funding. During the program, attendees will hear talks and discussions from experienced investigators and program officers. Attendees will have the opportunity to learn about:

  • The peer review process
  • Reaching out to program officers
  • Common errors
  • Important considerations
  • Funding for experimental organisms
  • Framing significance and novelty

Advanced Registration Required




 
Wednesday, March 27  
7:00 p.m. – 9:00 p.m.
Dallas Ballroom (Conference Center 1st Floor)

Opening General Session



Presentations:

7:00    Welcome. Michael Buszczak

7:20    Larry Sandler Award Presentation. Daniel Barbash

7:25    Larry Sandler Award Talk.

7:55    Keynote Introduction. Harmit Malik

8:00    What’s love got to do with it? Stimulating reproduction and activating eggs in Drosophila. Mariana Wolfner


 
Thursday, March 28  
8:30 a.m. – 12:00 noon
Dallas Ballroom (Conference Center 1st Floor)

Plenary Session I

Session Chair:  
Rachel Cox, Uniformed Services University of the Health Sciences

Presentations:

1 - 8:30    Image Award Presentation. Nasser Rusan

2 - 8:35    Assembly and disassembly of germ plasm localized RNPs. Elizabeth Gavis

3 - 9:05    The I of the fly. Bassem Hassan

4 - 9:35    The gut microbiome: the driving and driven partners of Drosophila. Angela Douglas

10:05 - Break

5 - 10:30    Interrogating centromere specification mechanisms. Barbara Mellone

6 - 11:00    Tissue growth and metabolic sensing: from flies to humans. Aurelio Teleman

7 - 11:30    Precision and plasticity in animal transcription. Angela DePace


 
Thursday, March 28  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Immunity and the Microbiome

Session Chairs:  
Neal Silverman, University of Massachusetts Medical School,
Nichole Broderick, University of Connecticut

8 - 4:30    Putting a STINGer on Drosophila: Evolutionary Conservation of Antimicrobial Defense. Alan Goodman

9 - 4:45    Tradeoffs between immune defense and resistance to environmental stress at a single amino acid polymorphism. Andrea Darby

10 - 5:00    Role of Circular RNAs in Innate Immunity and Neurodevelopment. Rui Zhou

11 - 5:15    Diet-induced microbiota adaptation is controlled by NF-kB-dependent regulation of 4EBP in Drosophila. Crissie Vandehoef

12 - 5:30    Modeling Host-Pathogen Interactions with the DNA virus IIV-6. Cara West

13 - 5:45    Two Nimrod receptors, NimC1 and Eater, synergistically contribute to phagocytosis in Drosophila melanogaster. Claudia Melcarne

14 - 6:00    A resilience function for the Toll pathway in host defense against systemic Aspergillus fumigatus infection. Dominique Ferrandon

197 - 6:15    A gut filling: The kinetics of the Wolbachia colonization in Drosophila guts. Natalie Vaisman

200 - 6:17    Investigating the microbiome’s role in female Drosophila melanogaster post-mating gene expression changes. Sofie Delbare

202 - 6:19    Microbiome transfers adaptive potential in Drosophila melanogaster. Lucas Henry

181 - 6:21    A tissue communication network coordinating innate immune response during muscle stress. Erika Geisbrecht


 
Thursday, March 28  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Evolution I

Session Chairs:  
Amanda Larracuente, University of Rochester,
Erin Kelleher, University of Houston,
Emily Behrman, Janelia Research Campus

15 - 4:30    Integrating cis and trans changes to analyze the evolution of Bcd dependent patterning network. Pinar Onal

16 - 4:45    Genetics and genomics of gene expression variation in the D. melanogaster early embryo. Nicolas Svetec

17 - 5:00    Convergent evolution of sex-limited pigmentation alleles in Drosophila. Emily Delaney

18 - 5:15    Recurrent losses and rapid evolution of the condensin II complex in insects. Thomas King

19 - 5:30    Patterns of genetic and transcriptional selection response under stress. Simon Forsberg

20 - 5:45    New gene formation in hybrid Drosophila. Rebekah Rogers

21 - 6:00    Adaptive evolution at a meiosis gene mediates species differences in the rate and patterning of recombination. Cara Brand

251 - 6:15    tartan underlies the evolution of male genital morphology. Alistair McGregor

257 - 6:17    Identifying the genetic changes driving network co-option during the evolution of a novel body part. Gavin Rice

254 - 6:19    Rapid evolution of a transcription factor essential for development in Drosophila. Bhavathanini Kasinathan

223 - 6:21    Meiotic drive and survival probability of newly inverted chromosomes. Spencer Koury


 
Thursday, March 28  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Models of Human Disease I

Session Chairs:  
Juan Botas, Baylor College of Medicine,
Rolf Bodmer, Sanford Burnham Prebys Medical Discovery Institute,
Georg Vogler, Sanford Burnham Prebys Medical Discovery Institute

22 - 4:30    Flies in the Diagnosis of Rare Disease: The Model Organisms Screening Center for the Undiagnosed Diseases Network. Michael Wangler

23 - 4:45    Zika virus protein NS4A inhibits Ankle2, a primary microcephaly locus that regulates asymmetric division. Nichole Link

24 - 5:00    Micropipette harpooning reveals a loss of physical coupling between the nucleus and cytoplasm in Drosophila models of muscular dystrophy. Lori Wallrath

25 - 5:15    The cathepsin Cystein protease-1/Cathepsin V regulates α-synuclein mediated accumulation and neurotoxicity in a synucleinopathy model. Tom Lee

26 - 5:30    Common and differential pathogenic mechanisms caused by mutant Huntington expression in glia and neurons. Tarik Onur

27 - 5:45    Hap40 is a conserved binding partner of HTT in Drosophila. Sheng Zhang

28 - 6:00    Phagocytic glia mediate prion-like spreading of mutant huntingtin aggregates in Drosophila brains. Margaret Pearce

770 - 6:15    The RNA export factor, Nxt1, is required for maintenance of muscle integrity, and for normal expression of mRNAs of genes that also generate circular RNAs. Helen White-Cooper

727 - 6:17    The PINK1/Parkin pathway mediates dominant mitochondrial toxicity in CHCHD10-induced ALS-FTD. Nam Chul Kim

730 - 6:19    UQCRC1 regulates neurodegeneration in a fly model of Parkinsonism. Yu-Chien Hung


 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Spotlight on Undergraduate Research



Organizers: 
Jennifer Jemc
Kimberly A. Carlson
Eric Stoffregen
 

7:45 pm Introduction

7:50 pm Zach Howard, Washington State University

Using the Drosophila Genetics Reference Panel to Identify Host Factors

Associated with Coxiella burnetii Infection

Research Mentor: Alan Goodman

8:05 pm Katherine Fisher, Indiana University

Investigation of smoke alarm in sensory neuron function and morphogenesis

Research Mentor: Stephanie Mauthner

8:20 pm Alyssa Jones, Stowers Institute

sina interactions during female meiosis

Research Mentor: R. Scott Hawley

8:35 pm Clara Poupault, University of Massachusetts Boston

Differential effects of vitamin A deprivation on different photoreceptor types

Research Mentor: Jens Rister

8:50 pm Arjun Rajan, University of Michigan-Ann Arbor

Characterization of the role of Similar to deadpan gene in Drosophila neural stem

cells

Research Mentor: Cheng-Yu Lee

9:05 pm Helen Stone, University of Virginia

Environment, but not thermosensation, dictates Drosophila melanogaster cold

hardening ability

Research Mentor: Alan Bergland

9:20 pm Research student and mentor networking


This session will highlight undergraduate research accomplishments from Drosophila research labs. Selected by faculty reviewers, student speakers will be selected by faculty reviewers to oral presentations on their projects. This undergraduate-specific session will demonstrate ways in which research has become an important part of the college experience through its integration into courses and mentoring in individual research labs.


 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Austin 2 (Hotel 2nd Floor)

Equity and inclusion in the Drosophila research community 



Organizers: 
Andrew Arsham
Cindy Arrigo    
Judith Leatherman

Universities, professional societies, and funding agencies recognize that inclusive research communities are more equitable, productive, and creative. Cultivating inclusion in classrooms, laboratories, and conferences requires discussion and intention to build a sustained effort. A shared space at the conference for Drosophila researchers to come together and learn from each other about inclusive practices is valuable to the health of our community. This workshop is for individuals from all career stages and institutional profiles with the goal of creating a dedicated space for open discussion of barriers to inclusion and strategies to mitigate them in support of inclusive research and teaching practices.




 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Pearl 4 (Hotel 2nd Floor)

Lipid signaling in development and disease:  Lessons from our fly



Organizers:
Francesca Di Cara
Andrew J. Simmonds
Agenda:  

7:45 pm Jason Karpac, College of Medicine, Texas A&M University, Utilizing Drosophila to explore the role of dietary lipids in shaping EGFR/Ras signaling by altering plasma membrane nanoscale proteolipid composition

8:00 pm Quan Yuan National Institute of Neurological Disorders and Stroke, National Institutes of Health, Isoform-specific transcriptional regulation of lipophorin receptors generate functional diversity

8:15 pm Andrew Simmonds, University of Alberta, Functional coordination between lipid droplets and peroxisomes

8:30 pm Julie Sellin, University of Bonn, Lysosomal cholesterol storage, autophagy and Hedgehog signalling

8:45 pm Nigel Griffiths, Brill laboratory, University of Toronto, and Cell Biology Program, The Hospital for Sick Children, Subcellular roles for the lipid phosphatase Sac1 during pigment cell morphogenesis

9:00 pm Margret Bülow, LIMES, University of Bonn, Peroxisomes in nutrient sensing

9:15 pm Matthew Sieber UT, Southwestern Medical Center, Examining the role of dietary lipids in intestinal stem cell differentiation

9:30 pm Francesca Di Cara, IWK Health Centre, Dalhousie University, Defining the lipid signalling in the innate immune responses

Lipids are the major energy storage molecules in the cells and have emerged as important signaling molecules in neurobiology, development and immunity. Despite a few basic metabolic pathways, we know very little about lipids. The main challenges are to identify specific lipid metabolites and understand their exact functions. Recently, increasing evidence proved that Drosophila models are highly valuable for lipid metabolism researches and notable progress have been made in defining lipid metabolic regulation during Drosophila development and in Drosophila models of human disease. The workshop will focus on recent progress that Drosophila is bringing to the field of lipid biology. 


 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Everything you ever wanted to know about sex 



Organizers:
Michelle Arbeitman
Rita Graze
Brian Oliver
Speakers:

Michelle N. Arbeitman, Florida State University

Erika A. Bach, New York University

Daniel A. Barbash, Cornell University

Li Zhao, Rockefeller University

Jonathan H. Massey, University of Michigan

Gavin R. Rice, University of Pittsburgh

Manyuan Long, University of Chicago
The workshop will cover the molecular genetics, development, neurobiology, genomics, evolution, and population genetics of sexual dimorphism, with an emphasis on cross-disciplinary interactions.  Presentations by invited speakers and selected abstracts from each discipline will be followed by moderated discussions.  The speakers are encouraged to summarize the key ideas behind their research for people working in other fields, outline the main unsolved questions, offer their opinions about future directions, and suggest connections that could be built with other disciplines.  


 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Austin 1 (Hotel 2nd Floor)

Intro to the Drosophila microbiome: How can I control the microbiome in my research?



Organizers:
John Chaston 
Robert Unckless
Agenda:
 

7:45 pm TBA, The Drosophila microbiota: Who’s there and what do they do?

8:00 pm Nichole Broderick, The University of Connecticut, The Drosophila microbiota and immunity. 

8:15 pm Drea Darby, Kansas University, Ecology, evolution, and the Drosophila microbiota. 

8:30 pm Will Ludington, Carnegie Institution for Science, Methods to study the Drosophila microbiota. 

8:45 pm Natalie Vaisman, Boston University, A gut filling: the kinetics of the microbiome.

8:55 pm Gerald Call, Midwestern University, Microbiome’s effect on development in a Drosophila Parkinson’s Disease model

9:05 pm Kristi Montooth, University of Nebraska-Lincoln, Interactions between the microbiota and metabolism

9:15 pm Andrei Bombin, The University of Alabama, The influence of natural diet and microbiota community on metabolic phenotype of Drosophila melanogaster

9:25 pm Luke Henry, Princeton University, Microbiomes modify adaptive potential in Drosophila melanogaster

9:35 pm Rich Meisel, University of Houston, Microbiomes and Immunity in Calyptrate Flies. 


The workshop is structured as a boot camp on the microbiome. The first half includes review lectures with key background information on the Drosophila microbiome. The second half includes short talks from researchers addressing how they're incorporating new microbiome work into their established research program. We anticipate discussion of problems and solutions.


 
Thursday, March 28  
7:45 p.m. – 9:45 p.m.
Austin 3 (Hotel 2nd Floor)

Designing a CRISPR-Cas9 undergraduate lab course to generate knock-in alleles for the research community



Organizer:
Alejandro D'Brot

CRISPR-Cas9 has become a staple in research labs, but has yet to be widely adopted in undergraduate lab courses. This workshop will equip educators how to design and lead a CRISPR-Cas9 undergraduate lab  course that aims to crowd-source the generation of attP-DsRed knock-in alleles for the Drosophila research community. We will also discuss how to adapt the course as an undergraduate training program for research labs. This workshop also provides a forum in which attendees will discuss course design, common pitfalls, time constraints and budget constraints. Professors who have previously lead a CRISPR-Cas9 lab course are encouraged to present.


 
Friday, March 29  
8:30 a.m. – 10:15 a.m.
Dallas Ballroom B (Conference Center 1st Floor)

Neural Development and Physiology

Session Chairs:  
Karen Chang, University of Southern California,
Robin Hiesinger, Free University Berlin,
Laura Alto, UT Southwestern Medical Center

39 - 8:30    Cell-type specific patterned stimulus-independent neuronal activity in the Drosophila visual system during synapse formation. Orkun Akin

40 - 8:45    Postsynaptic differentiation controlled by a specific Pix isoform mediates scaling growth of the neuromuscular junction. Cheuk Ho

41 - 9:00    Post-transcriptional regulation by Syncrip/hnRNP Q modulates activity-dependent synaptic plasticity at the larval NMJ. David Ish-Horowicz

42 - 9:15    Effects of altered gravity on the central nervous system of Drosophila melanogaster. Siddhita Mhatre

43 - 9:30    Hereditary Spastic Paraplegia proteins model a continuous dynamic network of ER tubules in Drosophila motor neurons. Cahir O'Kane

44 - 9:45    Hox miRNAs: tuning behavior to gene regulation. Daniel Garaulet

658 - 10:00    Tao negatively regulates retrograde BMP signaling during neuromuscular junction development in Drosophila. Pam Vanderzalm

646 - 10:02    The role of Rab11 GTPase in neuronal pruning of Drosophila sensory neurons. Hao-Hsiang Kao

661 - 10:04    Expansion Microscopy(ExM) enables subcellular localization of neurotransmitter receptors to single neurites in the neurons of the Drosophilamotion vision pathway. Edward Rogers

680 - 10:06    Contribution of Phosphatidylserine Exposure in Engulfment of Dendrite Debris by Phagocytes. Hui Ji


 
Friday, March 29  
8:30 a.m. – 10:15 a.m.
Dallas Ballroom D (Conference Center 1st Floor)

Regulation of Gene Expression I

Session Chairs:  
Michael Eisen, University of California, Berkeley,
Scott Barolo, University of Michigan

45 - 8:30    Continued activity of the pioneer factor Zelda is required to drive zygotic genome activation. Tyler Gibson

46 - 8:45    Promoter-specific histone methylation and post-transcriptional regulation of the foraging gene modulate food-associated behavior in Drosophila. Ina Anreiter

47 - 9:00    Investigating cis-regulatory evolution in Drosophila: Learning the rules of regulatory logic. Alexandra Buffry

48 - 9:15    A novel tudor-domain protein promotes germline differentiation through post-transcriptional gene regulation in cytoplasmic RNA granules. Caitlin Pozmanter

49 - 9:30    The contributions of optimal and suboptimal Bcd and Otd DNA binding sites to enhancer activity in the Drosophila embryo. Rhea Datta

50 - 9:45    Activating and repressing stochastic gene expression between chromosomes. Chaim Chernoff

366 - 10:00    Using Spineless gene expression to understand the Mechanisms of Transvection. Adrienne Chen

362 - 10:02    CrebA directly activates regulators of secretion. Dorothy Johnson

365 - 10:04    A novel role for Blimp-1 in the transcriptional repression of the Hippo pathway in postmitotic photoreceptors. Joseph Bunker

384 - 10:06    Distinct patterns of combinatorial regulation by isoforms of the ETS activator Pointed confer specificity to retinal cell fate acquisition. Chudong Wu


 
Friday, March 29  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Neural Circuits and Behavior I

Session Chairs:  
William Joiner, University of California, San Diego,
Ellie Heckscher, University of Chicago,
Yi-Wen Wang, University of Chicago

51 - 10:45    Visual detection of parasitoid wasps is mediated through the lobula columnar 11 neurons. Shaun Davis

52 - 11:00    Regulation of modulatory cell activity across olfactory neuropil in Drosophila melanogaster. Quentin Gaudry

53 - 11:15    Starvation differentially modulates GABA signaling in olfactory receptor neurons. Eryn Slankster

54 - 11:30    Feeding control via multimodal taste integration in pharyngeal taste neurons in adult Drosophila. Yu-Chieh Chen

55 - 11:45    What makes a meal? Defining meals from bouts and identifying regulators of meal size. Scarlet Park

56 - 12:00    The nervy gene modulates aggression levels through its function in the octopaminergic neurons. Kenta Asahina

690 - 12:15    The neural circuitry of learning dialects in Drosophila species. Balint Kacsoh

713 - 12:17    Investigation of neural circuits that mediate acquisition of new knowledge. Daisuke Hattori

722 - 12:19    Bidirectional opponent thermosensors orchestrate euthermic regulation via cross-inhibition. Luis Hernandez Nunez

720 - 12:21    Neuroligin3 is required for a response to the social environment in Drosophila melanogaster. Ryley Yost


 
Friday, March 29  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Physiology, Metabolism and Aging I

Session Chairs:  
Tânia Reis, University of Colorado Medical School,
Akhila Rajan, Fred Hutch,
Elizabeth Rideout, The University of British Columbia

57 - 10:45    FOXO is a hypoxia-inducible transcription factor necessary for Drosophila tolerance to low oxygen. Elizabeth Barretto

58 - 11:00    Drosophila HNF4 directs a switch in fatty acid metabolism that supports the transition to adulthood. Gilles Storelli

59 - 11:15    Analysis of the Diurnal Transcriptomes of Young and Old Drosophila Heads Reveals Metabolic Shifts During Aging. David Hendrix

60 - 11:30    Genome-wide analyses of lifespan and healthspan reveal a role for decima as a novel regulator of neuronal insulin-like peptide production. Kenneth Wilson

61 - 11:45    Neural mechanisms underlying energy homeostasis: hormonal regulation of synaptic plasticity in fat-sensing neurons. Ava Brent

62 - 12:00    Peroxisome-mediated inter-tissue communication during Drosophila aging. Kerui Huang

617 - 12:15    Octopamine Receptors OAMB and Octβ2R are Required in Muscle for Exercise Adaptations. Alyson Sujkowski

627 - 12:17    Neuropeptide F receptor acts in the Drosophila prothoracic gland to regulate body size and developmental timing. Jade Kannangara

606 - 12:19    Sustaining mitochondrial genome integrity and robustness with age. Pei-I TSAI

615 - 12:21    Regulation of Lifespan by dSirt6 in Drosophila melanogaster. Jackson Taylor


 
Friday, March 29  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Regulation of Gene Expression II/ Chromatin, Epigenetics and Genomics I

Session Chairs:  
Michael Eisen, University of California, Berkeley,
Scott Barolo, University of Michigan,
Xin Chen, Johns Hopkins University,
Erica Larschan, Brown University,
Leila Rieder, Emory University

63 - 10:45    The Drosophila pioneer factor Zelda modulates the nuclear microenvironment of a Dorsal target enhancer to potentiate transcriptional output. Peter Whitney

64 - 11:00    Regulatory crosstalk between ecdysone-induced transcription factors confers temporal specificity to chromatin-state & gene expression during metamorphosis. Spencer Nystrom

65 - 11:15    Trans regulatory changes produce differences in maternal transcript deposition between closely related species of Drosophila. Emily Cartwright

66 - 11:30    Dynamic identification of the dosage-compensated Drosophila male X-chromosome during early embryogenesis. Leila Rieder

67 - 11:45    Unidirectional fork movement coupled with strand-specific histone incorporation ensures asymmetric histone inheritance. Matthew Wooten

68 - 12:00    The global, multilayer structure of homolog pairing reflects a level of functional organization in the Drosophila genome. Jumana AlHaj Abed

390 - 12:15    Brain-wide screen for protein and mRNA localization reveals that multiple post-transcriptional mechanisms contribute to synaptic protein enrichment. Josh Titlow

379 - 12:17    A tsRNA-AGO1 autoregulatory feedback loop. Feng He

406 - 12:19    Histone 3 lysine 14 is essential and required for wing patterning in Drosophila. Mattias Mannervik

408 - 12:21    Dynamics of free and chromatin-bound histone H3 during early embryogenesis. Amanda Amodeo


 
Friday, March 29  
2:15 p.m. – 4:15 p.m.
Austin 1 (Hotel 2nd Floor)

Collaborating with clinical researchers: expanding opportunities for Drosophila biologists in rare disease diagnosis and therapeutic research 



Organizers:
Shinya Yamamoto
Jamie M. Kramer    
Paul C. Marcogliese
The goal of this workshop is to increase the awareness of exciting opportunities for Drosophila biologists to be directly involved in clinical research. The Undiagnosed Diseases Network (UDN) and Rare Diseases Models & Mechanisms Network (RDMM) are using Drosophila to assess functions of genetic variants found in patients with rare diseases, understand disease mechanisms, and develop models to explore potential treatments. By sharing the lessons learned from researchers who have been collaborating with physicians and introducing web-based tools that can facilitate the identification of potential clinical collaborators, we hope to encourage Drosophila researchers to proactively engage in cross-disciplinary medical research.
 

2:15pm Shinya Yamamoto, Baylor College of Medicine, Introduction of the purpose and goal of the workshop

2:18pm Stephanie E. Mohr, Harvard Medical School, First in Fly: the role of Drosophila in biomedical research

2:33pm  Paul C. Marcogliese, Baylor College of Medicine, Collaborating with clinicians in the Undiagnosed Diseases Network in the USA

2:48pm Jamie M. Kramer, Western University, Collaborating with clinicians in the Rare Disease Models and Mechanisms Network in Canada

3:03pm Erdem Bangi, Florida State University, Drug discovery using Drosophila in academia

3:18pm Nina DiPrimio, Perlara, Drug discovery using Drosophila in industry

3:33pm Ming Guo, MD, UCLA, Bridging the basic science and clinical fields

3:48pm Julia Wang, Baylor College of Medicine, Navigating MARRVEL and GeneMatcher: online resources that facilitate collaborative research

4:03 Panel Discussion (speakers and audience, modulated by Shinya Yamamoto)

4:15 End




 
Friday, March 29  
2:15 p.m. – 4:15 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Feeding Behavior, Nutrition and Metabolism 



Organizers:
Tânia Reis    
William W. Ja
 

2:15 pm Pankaj Kapahi, The Buck Institute, Dietary restriction enhances circadian amplitude and delays visual decline by enhancing phototransduction

2:30 pm Andrew Butts, University of Utah, Altered actin filament dynamics in the Drosophila mushroom bodies lead to fast acquisition of alcohol consumption preference

 

2:45 pm Tetsuya Miyamoto, Texas A&M, Neuronal gluconeogenesis regulates systemic glucose homeostasis

 

3:00 pm Xiaobing Bai, University of Chinese Academy of Sciences, CNS insulin signaling regulates feeding behavior and protein homeostasis in adult fruit flies

 

3:15 pm Xinsheng Gao, Texas A&M, CDK8-CycC mediates the dietary effects on developmental timing in Drosophila larvae

 

3:30 pm Katherine Beebe, University of Utah, Regulation of adult lipid homeostasis by Drosophila Estrogen-Related Receptor

 

3:45 pm Jason M. Tennessen, Indiana University, Bloomington, When an oncometabolite isn’t an oncometabolite: endogenous L-2-hydroxyglutarate production is widespread among Dipteran insects and regulates the hypoxia response.

 

4:00 pm Wei Song, Wuhan University, Tumor-Derived Upd3 Couples Tumor Growth and Host Wasting

 


Drosophila has emerged as a powerful model system for studying how diet and nutrition can influence a wide range of metabolic processes. This workshop is designed to assemble a diverse group of presentations that highlight recent advances in the field of nutrition and metabolism. The goal of this workshop is to foster discussions and encourage collaborations among individuals interested in topics ranging from food intake as a fundamental parameter of metabolism to the effects of diet on energy storage and utilization.


 
Friday, March 29  
2:15 p.m. – 4:15 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Developmental Mechanics



Organizers:
Rodrigo Fernandez-Gonzalez
Guy Tanentzapf    
Adam Martin
Agenda:

2.15-2.35pm: Dan Bergstralh, University of Rochester, Epithelial Cell Reintegration: The Ins and Outs.

2.35-2.55pm: Ruth Johnson, Wesleyan University, Patterning the Drosophila pupal eye: finding new answers to old questions.

2.55-3.15pm: Gregory Emery, Institute for Research in Immunology and Cancer - Universite de Montreal, The Ste20 kinase Misshapen coordinates propulsive and contractile forces during collective cell migration.

3.15-3.35pm: Jocelyn McDonald, Kansas State University, Protein Phosphatase 1 activity controls a balance between single cell and collective cell motility in vivo.

3.35-3.55pm: Mitsutoshi Nakamura, Fred Hutchinson Cancer Research Center, Regulation of actin dynamics in cell wound repair.

3.55-4.15pm: Elizabeth Chen, UT Southwestern Medical Center, Mechanical tension drives cell membrane fusion.

Developmental biology has undergone a revolution over the last two decades, largely as a result of work in Drosophila, that placed biomechanical, quantitative imaging, and mathematical modeling approaches at the forefront of the study of tissue morphogenesis. In particular, the establishment of tools to measure and manipulate mechanical forces in living organisms has demonstrated that mechanical forces profoundly shape animal development. In this workshop, we will review the most recent technical advances to visualize and quantify force generation in Drosophila, and we will discuss the latest results demonstrating the interplay between physical forces, molecular dynamics and tissue morphogenesis.


 
Friday, March 29  
2:15 p.m. – 4:15 p.m.
Austin 3 (Hotel 2nd Floor)

Using Drosophila to bring authentic course-based undergraduate research experiences (CUREs) into the undergraduate classroom



Organizers:
Afshan Ismat 
Andy Arsham   
Justin DiAngel
Agenda:
 

2:15     Afshan Ismat, University of St. Thomas, Introductory remarks

2:18     Andy Arsham, Bemidji State University, Genetics

2:21     Karen Hales, Davidson College, Genetics

2:24     Rebecca Delventhal and Josefa Steinhauer, Yeshiva University, Genetics

2:27     Nancy Pokrywka, Vassar College, Cell Biology

2:30     Alder Yu, University of Wisconsin-La Crosse, Molecular Biology

2:33     Justin DiAngelo, Penn State Berks, Biochemistry

2:36     Afshan Ismat, University of St. Thomas, Developmental Biology

2:39     Laura Reed, University of Alabama, Genomics Education Partnership

2:45     Small group work

3:45     Small groups report back to larger group


This workshop is designed to help instructors at Primarily Undergraduate Institutions (PUIs) bring authentic research experiences using Drosophila into the undergraduate classroom.  Attendees will split into small groups and spend time creating semester-long experimental protocols that can be adapted to answer a variety of research questions.  This workshop will focus on both the experimental approaches and the scientific questions, both of which are essential elements of a successful CURE.


 
Friday, March 29  
2:15 p.m. – 4:15 p.m.
Austin 2 (Hotel 2nd Floor)

Maximize the impact of your curriculum vitae and resume workshop



Whether applying for a fellowship, funding, or position how you frame your accomplishments in your curriculum vitae and resume is important.

  • Learn tips and tricks to communicate who you are as a scientific professional.
  • Workshop your curriculum vitae or resume during the event.

To get the most out of the event, all attendees should bring a recent copy of their curriculum vitae or resume to the workshop.




 
Friday, March 29  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Models of Human Disease II

Session Chairs:  
Juan Botas, Baylor College of Medicine,
Rolf Bodmer, Sanford Burnham Prebys Medical Discovery Institute,
Georg Vogler, Sanford Burnham Prebys Medical Discovery Institute

69 - 4:30    A personalized approach to treat a KRAS mutant colorectal cancer patient using Drosophila. Erdem Bangi

70 - 4:45    Diet-enhanced Drosophila Tumors Induce Muscle Wasting as a Nutrient-Scavenging Metabolic Program. Holly Newton

71 - 5:00    A tumor-microbe self-enforcing loop promotes intestinal tumorigenesis. Jun Zhou

72 - 5:15    Transgenerational inheritance model of high fat diet-induced lipotoxic cardiomyopathy. Maria Guida

73 - 5:30    A conserved role for the N-glycosylation pathway in sleep and seizures. Brittany Leger

74 - 5:45    The intellectual disability-associated SWI/SNF chromatin remodeling complex regulates structural plasticity of the Drosophila mushroom body during critical developmental transitions. Jamie Kramer

75 - 6:00    A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Masahiro Sonoshita

739 - 6:15    The microbiome's effect on the pathogenesis of Alzheimer's disease. Michael Zhu

748 - 6:17    Late-breaking news: Autophagy goes on strike! – Rampant immune response kills neurons! Arvind Shukla

723 - 6:19    Loss-of-Function Variants in IRF2BPL are Associated with Neurological Phenotypes. Paul Marcogliese

766 - 6:21    Multi-Model System Approach to Identifying Atrial Fibrillation Genes and Mechanisms. James Kezos


 
Friday, March 29  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Physiology, Metabolism and Aging II

Session Chairs:  
Tânia Reis, University of Colorado Medical School,
Akhila Rajan, Fred Hutch,
Elizabeth Rideout, The University of British Columbia

76 - 4:30    Phosphatidic acid as a limiting host metabolite for the proliferation of the microsporidium Tubulinosema ratisbonensis in Drosophila flies. Dominique Ferrandon

77 - 4:45    Drosophila rab27 mediates longevity in mushroom body by downregulating TOR signaling. Yi-Jhan Li

78 - 5:00    With no lysine (WNK) Kinase: A Potassium Sensor. John Pleinis

79 - 5:15    An intestinal zinc sensor couples micronutrient availability with developmental growth through Tor signalling. Siamak Redhai

80 - 5:30    Drosophila melanogaster sex peptide is a key regulator of female midgut morphology and physiology. Melissa White

81 - 5:45    Activity of the nuclear receptor Seven up in different tissues controls distinct processes of oogenesis. Lesley Weaver

82 - 6:00    Male-female differences in Dilp2 secretion contribute to sexual size dimorphism in Drosophila. Elizabeth Rideout

621 - 6:15    Cellular heterogeneity underlying poly-functional fat body tissue in Drosophila melanogaster. Vanika Gupta

580 - 6:17    Mir-969 regulates body fat mass through Gr47b. Jin Seo

584 - 6:19    The role of RNA-binding protein alan shepard in whole organism metabolism regulation. Claire Gillette

634 - 6:21    Epigenetic Inheritance of Alcohol Sensitivity in Drosophila melanogaster. Jasmina Abdalla


 
Friday, March 29  
4:30 p.m. – 6:30 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Neural Development and Physiology II/Neural Circuits and Behavior II

Session Chairs:  
Karen Chang, University of Southern California,
Robin Hiesinger, Free University Berlin,
William Joiner, University of California, San Diego,
Ellie Heckscher, University of Chicago,
Yi-Wen Wang, University of Chicago,
Laura Alto, UT Southwestern Medical Center

83 - 4:30    Stromalin constrains memory acquisition by developmentally limiting synaptic vesicle pool size. Anna Phan

84 - 4:45    Timing temporal transitions during brain development. Anthony Rossi

85 - 5:00    The beta-alanine transporter BalaT localizes to visual lamina and sustains vision in extended light conditions. Andrew Moehlman

86 - 5:15    Sleep need is driven by a neural circuit involving stress-sensing peripheral neurons and the central brain. William Joiner

87 - 5:30    The non-nuclear splice isoform of NFκB gene Dif modulates sensitivity to ethanol sedation in Drosophila melanogaster. Thilini Wijesekera

88 - 5:45    Serotonergic modulation of goal-directed habituation during exploration in Drosophila. Miguel de la Flor

89 - 6:00    Secrets of the zombie fly: Determining the neurological basis of behavioral manipulation in Drosophila. Carolyn Elya

679 - 6:15    Dscam regulates lineage dependent repulsion during columnar unit formation in the medulla. Chuyan Liu

656 - 6:17    The Transcription Factor Gooseberry, a pax3/pax7 homolog, interacts with Wingless to control neuronal function. Marizabeth Perez

688 - 6:19    The neuronal design underlying consolidated Anesthesia-Resistance Memory (ARM). Emmanuel Antwi-Adjei

683 - 6:21    Dopamine deficiency: how dopaminergic circuits compensate for loss of dopamine. Ryan Sangston


 
Saturday, March 30  
8:30 a.m. – 10:15 a.m.
Dallas Ballroom A (Conference Center 1st Floor)

Cell Biology: Cytoskeleton, Organelles, Trafficking

Session Chairs:  
Elizabeth Chen, UT Southwestern Medical Center,
Blake Riggs, San Francisco State University,
Donghoon Lee, UT Southwestern Medical Center

90 - 8:30    Crk adaptor protein containing multiprotein signaling complexes regulate actomyosin-dependent developmental processes. Andrew Spracklen

91 - 8:45    Proteomic analysis of ovarian ring canals reveals the mechanism of ubiquitin-mediated regulation of the F-actin cytoskeleton. Lynn Cooley

92 - 9:00    The significance of sequestering H2A, H2Av and H2B on lipid droplets. Roxan Stephenson

93 - 9:15    Mechanotransduction at tricellular junctions. Huapeng Yu

94 - 9:30    Wash functions in the nucleus to affect Nuclear Envelope budding. Jacob Decker

95 - 9:45    Spectraplakin Shot maintains perinuclear microtubule organization in polyploid cells. Tianhui Sun

542 - 10:00    The p38 MAP kinase is critical for rapid embryonic wound closure. Gordana Scepanovic

528 - 10:02    Regulation of Mitochondrial Network Organization in Drosophila Muscles. Prasanna Katti

517 - 10:04    Endocytosis regulates Fog signaling to promote apical constriction during Drosophila salivary gland invagination. Thao Le

549 - 10:06    Tubulin polymerization promoting protein, Ringmaker, and microtubule associated protein 1B homolog, Futsch, coordinate microtubule organization and synaptic growth. Swati Banerjee


 
Saturday, March 30  
8:30 a.m. – 10:15 a.m.
Dallas Ballroom B (Conference Center 1st Floor)

Chromatin, Epigenetics and Genomics II

Session Chairs:  
Xin Chen, Johns Hopkins University,
Erica Larschan, Brown University,
Leila Rieder, Emory University

96 - 8:30    Epigenetic effects of transposable elements in 3D nuclear space impact genome function. Grace Lee

97 - 8:45    The polycomb silencing switch during germline development. Steven DeLuca

98 - 9:00    H3K9me3-mediated gene silencing and female fate maintenance in Drosophila germ cells. Helen Salz

99 - 9:15    Satellite DNA Regulation in Drosophila melanogaster. Xiaolu Wei

100 - 9:30    Diversification and collapse of the Drosophila telomere elongation mechanism. Bastien Saint-leandre

101 - 9:45    Chromatin reprogramming by the histone H3.3 K27M oncomutation during DNA replication. Kami Ahmad

412 - 10:00    Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation. Daniel McKay

413 - 10:02    Centromere organization and evolution in the simulans clade. Amanda Larracuente

431 - 10:04    An evolutionary perspective on gene expression and regulatory dynamics at the single-cell level. Li Zhao

430 - 10:06    Meiotic sex chromosome inactivation in the Drosophila melanogaster male germ line. Miriam Akeju


 
Saturday, March 30  
8:30 a.m. – 10:15 a.m.
Dallas Ballroom D (Conference Center 1st Floor)

Signal Transduction

Session Chairs:  
Jessica Treisman, NYU School of Medicine,
Ken Moberg, Emory Univ School of Medicine,
Helen Attrill, University of Cambridge

102 - 8:30    A membrane transporter is required for steroid hormone uptake in Drosophila. Naoki Yamanaka

103 - 8:45    Patronin regulates organ growth through Hippo signaling pathway in Drosophila. Dae-Wook Yang

104 - 9:00    Regulation of epidermal cell differentiation by the Hippo pathway. Heya Zhao

105 - 9:15    Chromatin modeling protein Hat-trick is a novel regulator of Notch signaling in Drosophila melanogaster. Ankita Singh

106 - 9:30    Making new connection between TOR, autophagy, and metabolism. Hong-Wen Tang

107 - 9:45    The TGF-β/Activin ligand Act-β, but not Dawdle, is required for survival under chronic nutrient deprivation. Heidi Bretscher

501 - 10:00    Suppression of store-operated calcium entry components dStim and dOrai results in dilated cardiomyopathy. Courtney Petersen

505 - 10:02    New signaling intensity-dependent regulation of the MAPK pathway revealed through an oncogenic KRAS Drosophila model. Jessica Sawyer

497 - 10:04    NF-κB Shapes Metabolic Adaptation by Attenuating Foxo-mediated Lipolysis in Drosophila. Maral Molaei

495 - 10:06    Wound-induced polyploidization is dependent on Intergrin-Hippo signaling. Rose Besen-McNally


 
Saturday, March 30  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Cell Death and Cell Stress

Session Chairs:  
Don Ryoo, New York University School of Medicine,
Gabor Juhasz, Eotvos Lorand University,
Tamas Maruzs, Biological Research Centre, Hungarian Academy of Sciences

108 - 10:45    Stabilized Acinus manages cellular stress by elevating basal levels of autophagy. Nilay Nandi

109 - 11:00    The sphingolipid-synthesizing enzyme infertile crescent engages crumbs for neuronal maintenance through redox signaling cascade. Fei-Yang Tzou

110 - 11:15    Drosophila G3BP, RASPUTIN, is sufficient but not necessary for stress granule formation in intestinal progenitor cells. Kasun Buddika Jayawardhana Koomangodage

111 - 11:30    Loss of Peroxisomal ACOX1 induces autoimmunity whereas a denovo gain of function variant induces elevated ROS and glial loss in humans and flies. Hyunglok Chung

112 - 11:45    Non-canonical translation initiation factors regulate the expression of ATF4 in response to cellular stress. Deepika Vasudevan

113 - 12:00    Damage to the basement membrane by ROS and JNK recruit hemocytes to overgrown tissue. Neha Diwanji

164 - 12:15    Analyzing the importance of ubiquitin-dependent selective protein aggrephagy in Drosophila. Gabor Juhasz

166 - 12:17    Loss of the ER metalloprotease CG14516 rescues retinal degeneration by reducing ER stress-induced apoptosis in a Drosophila model of retinitis pigmentosa. Rebecca Palu

174 - 12:19    Ionizing radiation induces regenerative properties in a caspase-dependent manner in Drosophila. TinTin Su

172 - 12:21    Follicle cell actin dynamics and calcium bursts during nurse cell death. Pelagia Candelas


 
Saturday, March 30  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Patterning, Morphogenesis and Organogenesis I

Session Chairs:  
Jennifer Zallen, HHMI/Sloan Kettering Institute,
Juan Riesgo-Escovar, Universidad Nacional Autónoma de México

114 - 10:45    The Alary Muscles. A keystone of the heart. Alain Vincent

115 - 11:00    The mechanisms of dynamin-actin interaction. Ruihui Zhang

116 - 11:15    Actomyosin cables prevent premature tissue internalization in the Drosophila embryo. Jessica Yu

117 - 11:30    Photoreceptor apical domain remodeling coordinates epithelial elongation during retinal morphogenesis. Xiao Sun

118 - 11:45    A new member of an elite group: Clamp as a novel regulator of Zygotic Genome Activation (ZGA) in Drosophila melanogaster embryos. Megan Colonnetta

119 - 12:00    Regulation of inductive signaling output by antiparallel morphogen gradients during epithelial patterning in the Drosophila ovary. Laura Nilson

481 - 12:15    Force-dependent tendinous ECM remodeling during flight muscle Development. Wei-Chen Chu

454 - 12:17    Mob family proteins and the nuclear Dbf2-related kinase, Tricornered, are required for tube formation in the ovarian follicular epithelium. Juan Duhart

452 - 12:19    The BTB/POZ domain factor Ribbon has a dual role as the transcriptional regulator of both organ growth and morphogenesis in the embryonic epithelium. Rajprasad Loganathan

447 - 12:21    Analysis of Defective Heart Patterning in akirin Mutants. Hayley Milner


 
Saturday, March 30  
10:45 a.m. – 12:30 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Stem Cells, Regeneration and Tissue Injury

Session Chairs:  
Susan Parkhurst, Fred Hutch,
Lucy Erin O'Brien, Stanford University School of Medicine,
Mitsutoshi Nakamura, Fred Hutch

120 - 10:45    “Survival of the fittest”: Determining the mechanism by which BenA causes hypercompetition in the follicle stem cell niche. Sumitra Tatapudy

121 - 11:00    A novel mutation in brain tumor causes both neural over-proliferation and neurodegeneration in adult Drosophila. Stanislava Chtarbanova

122 - 11:15    Shavenbaby isoforms orchestrate the proliferation versus differentiation switch of intestinal stem cells. Sandy Al hayek

123 - 11:30    Hematopoietic “Intermediate Progenitors” represent a distinct and novel cell type that marks the transition of a true progenitor to a differentiated fate. Carrie Spratford

124 - 11:45    Local role for steroids in regenerative growth in Drosophila. Douglas Terry

125 - 12:00    Evolutionarily conserved Wingless signaling pathway is regulated by newly identified Newt genes to trigger regeneration response in Drosophila. Abijeet Mehta

286 - 12:15    Caliban regulates mitochondria integrity to maintain intestine homeostasis. Xiaolin Bi

291 - 12:17    TGFβ/Activin signaling is a switch between homeostasis and stem cell regeneration in the Drosophila testis. Salvador Herrera

288 - 12:19    An SH3PX1-dependent endocytosis/autophagy network restrains intestinal stem cell proliferation by counteracting EGFR signaling. Peng Zhang


 
Saturday, March 30  
4:00 p.m. – 6:00 p.m.
Dallas Ballroom B (Conference Center 1st Floor)

Evolution II

Session Chairs:  
Amanda Larracuente, University of Rochester,
Erin Kelleher, University of Houston,
Emily Behrman, Janelia Research Campus

126 - 4:00    Functional analysis of de novo evolved genes in male Drosophila reproduction. Brendan Kelly

127 - 4:15    Save our sons: Surprising roles for RNAi to resolve intragenomic sex chromomsome conflict. Chun-Ming Lai

128 - 4:30    Diapause-associated SNPs vary clinally but not seasonally in natural populations of D. melanogaster. Priscilla Erickson

129 - 4:45    Genotype-by-temperature interactions maintain polygenic sex determination in the housefly. Kiran Adhikari

130 - 5:00    X-chromosome meiotic drive in Drosophila simulans: Genetic basis drive suppression. Cécile Courret

131 - 5:15    Male recombination created geographically distributed haplotypes of the young neo-Y chromosome of Drosophila albomicans. Kevin Wei

132 - 5:30    Host-virus co-evolution in Drosophila innubila highlights non-RNAi pathways as key to antiviral response. Tom Hill

249 - 5:45    Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations. Cory Weller

217 - 5:47    Trans-complementing system uncovers fine workings of CRISPR-based gene drives. Victor Lopez del Amo

210 - 5:49    CRISPR Knockout and Functional Analysis of Three Y Chromosome Genes in D. melanogaster. Yassi Hafezi

245 - 5:51    Fitness consequences of long sperm and sperm storage organs of Drosophila melanogaster. Halli Weiner


 
Saturday, March 30  
4:00 p.m. – 6:00 p.m.
Dallas Ballroom A (Conference Center 1st Floor)

Patterning, Morphogenesis and Organogenesis II

Session Chairs:  
Jennifer Zallen, HHMI/Sloan Kettering Institute,
Juan Riesgo-Escovar, Universidad Nacional Autónoma de México

133 - 4:00    Precise regulation of RhoA promotes proper tissue curvature. Adam Martin

134 - 4:15    Crumbs-complex directed apical membrane dynamics controls epithelial cell ingression. Sergio Simoes

135 - 4:30    The LRR receptor Tartan establishes polarity at tissue compartment boundaries during convergent extension. Adam Pare

136 - 4:45    Linking tissue morphogenesis and patterning to the data mining framework: a proposal and a proof of concept. Tomer Stern

137 - 5:00    Septate junction proteins maintain tissue integrity during dorsal closure. Clinton Rice

138 - 5:15    Septate junctions coordinate epithelial integration with growth of stem cell progeny during intestinal turnover. Paola Moreno-Roman

139 - 5:30    A quantitative analysis of EGFR dynamics during early Drosophila development. Nicole Revaitis

465 - 5:45    Tissue-scale mechanical coupling reduces morphogenetic noise to ensure precision during epithelial folding. Anthony Eritano

444 - 5:47    Wingless counteracts epithelial folding in Drosophila wing discs by increasing mechanical tension at basal cell edges. Liyuan Sui

440 - 5:49    Growth Regulatory Pathway collaborates with Axial Patterning Genes to regulate Patterning and Growth in Drosophila Eye. Neha Gogia

463 - 5:51    Feedback between actomyosin and microtubules stabilizes intercellular force transmission during tissue folding. Clint Ko


 
Saturday, March 30  
4:00 p.m. – 6:00 p.m.
Dallas Ballroom D (Conference Center 1st Floor)

Reproduction and Gametogenesis

Session Chairs:  
Hilary Ashe, University of Manchester,
Erika Bach, New York University School of Medicine,
Salvador Herrera, New York University School of Medicine

140 - 4:00    The Dynamics of Germline Mutations and DNA Repair in Single-cell RNA-seq of Adult Drosophila Testis. Evan Witt

141 - 4:15    GCNA preserves genome integrity and fertility across species. Courtney Goldstein

142 - 4:30    Centromere clustering promotes meiotic homolog pairing. Talia Hatkevich

143 - 4:45    Neuropeptide Dh31 signaling regulates early germline cyst survival during adult Drosophila oogenesis. Tianlu Ma

144 - 5:00    Epithelial cell gene expression and function during developmental nurse cell clearance in Drosophila melanogaster ovaries. Diane Lebo

145 - 5:15    Sex-specific specification of the follicle stem cells in the developing Drosophila ovary. Abigail Dove

146 - 5:30    Adaptive evolution of piRNA pathway proteins affects piRNA biogenesis but not TE transcripts. Luyang Wang

347 - 5:45    Directing testis specific gene expression: Nucleosome dynamics and transcriptional regulators. Katia Jindrich

352 - 5:47    A robust transposon-domesticating response from germline stem cells. Sungjin Moon

351 - 5:49    Drosophila accessory gland secondary cells and post-mating sperm dynamics. Ben Hopkins

303 - 5:51    Dm Ime4 is required for somatic cyst cell permeability barrier function during spermatogenesis. Antonio Rockwell


 
Saturday, March 30  
7:30 p.m. – 9:30 p.m.
Dallas Ballroom (Conference Center 1st Floor)

Techniques & Technology

Session Chairs:  
Hugo Bellen, Baylor College of Medicine,
Lena Riabinina, University of Manchester, UK,
Julie Simpson, University of California, Santa Barbara

Presentations:

147 - 7:30    New Tools and Methods for Neuronal Circuit Analysis in Drosophila. Gerald Rubin

148 - 7:45    Spying on the dynamics of acetylcholine, dopamine, octopamine, and 5-HT in fly’s brain by constructing new genetically-encoded GRAB sensors. Yulong Li

149 - 8:00    Selectable, drug-based genetics and transgenesis in Drosophila melanogaster. Nick Matinyan

150 - 8:15    Bellymount: A novel, method for longitudinal, intravital imaging of abdominal organs in adult Drosophila. Leslie Ann Koyama

151 - 8:30    GAL4s, LEGOs, and 3D-printers: the genetic toolbox of the 21st century Drosophilist. Giorgio Gilestro

152 - 8:45    Techniques and computational methods for single-cell regulatory genomics in Drosophila. Stein Aerts

153 - 9:00    FlyBase updates presentation. Steven Marygold

154 - 9:15    A Gene Disruption Project (GDP) update: using CRISPR with PCR-generated homology donors to knock-in Swappable Integration Cassettes in introns of genes in flies and in S2 cells. Oguz Kanca


 
Sunday, March 31  
8:30 a.m. – 12:00 noon
Dallas Ballroom (Conference Center 1st Floor)

Plenary II

Session Chair:  
Helmut Kramer, UT Southwestern

Presentations:

155 - 8:30    p53 genes and the game of transposons. John Abrams

156 - 9:00    Neural mechanisms for dynamic acoustic communication. Mala Murthy

157 - 9:30    Y chromosome evolution in 400 Drosophila species. Bernardo Carvalho

10:00 - Break

158 - 10:30    Waking up “Sleeping” Neural Stem Cells. Hongyan Wang

159 - 11:00    Towards a brain architecture for visual behavior selection. Gwyneth Card

160 - 11:30    Upstream regulation of Hippo signaling in epithelial cells. Rick Fehon

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